Skin Logic Aesthetics and Laser Clinic Logo

020 3442 0058

Polynucleotides and Purasomes Exosomes Facial Rejuvenation Therapy London

Polynucleotides
Skin Boosters

Need help choosing?

Meet with one of our expert providers for a free consultation.
Book a Free Consultation →

From

£375

Third Generation Polynucleotides Skin Boosters

  • Nucleofill
  • Crystal PDRN
  • Rejuran Healer
  • Philart

Polynucleotides Skin Booster injectable, is a new concept in regenerative medicine which, when injected promote cell turnover, improve skin hydration and elasticity, heal damage caused by UV rays and improve photoaging and acne scarring. This innovative treatment harnesses the power of DNA fragments to revitalise your skin from within, offering a natural and long-lasting solution to various skin concerns.

Treatment Duration

45 Mins

Results Seen

Gradual improvement

Results Lasts

Up to 6 Months

Recovery Time

Almost None

Polynucleotides Skin Boosters are advanced injectable treatments that use DNA fragments derived from salmon or trout sperm to improve skin quality, hydration, and overall appearance. These DNA fragments play a crucial role in cellular regeneration and tissue repair, offering a natural approach to skin rejuvenation.

Polynucleotides (PDRNs) are ultrapure DNA fractions, which stimulate skin rejuvenation at the cellular level. They also have an anti-free radical action, scavenging damaging OH hydroxyl radicals, which can accumulate as a result of cell damage from external pollution, stress and UV rays.

Once Polynucleotides have been filtered and purified, the DNA fractions within when expertly injected in to the mid dermis, initiate your body’s own natural fibroblast production which results in a thicker, healthier epidermis (up to 52% in 23 days) and increased collagen production (up to 47% in 23 days). Inflammation is reduced and a more youthful volume and skin hydration is restored.

  • Nucleofill
  • Crystal PDRN
  • Rejuran Healer
  • Philart

Benefits of Polynucleotides Skin Boosters

Choosing Polynucleotides Skin Booster treatments at our London Harley Street clinic offers numerous advantages:

  • Natural Skin Regeneration: Stimulates your skin’s own repair mechanisms
  • Improved Skin Quality: Enhances overall skin texture, firmness, and radiance
  • Deep Hydration: Boosts skin moisture levels from within
  • Natural-Looking Results: Achieves a subtle, refreshed appearance
  • Versatile Treatment: Can be used on face, neck, décolletage, and hands
  • Minimal Downtime: Return to daily activities immediately after treatment
  • Customisable: Treatments can be tailored to your unique skin needs and goals
Polynucleotides Skin Boosters London
Rotating Skin Logic Icon

Indications

  • Skin’s laxity and ageing with poor circulation
  • Dehydrated, rough and inflamed skin
  • Sun damaged and subjected to oxidative stress (ie smoking and other unhealthy lifestyle choices such as high sugar intake) skin
  • Dark circles under eyes and post inflammatory pigmentation
  • Scars at any stage
  • Skin hydration
  • Lifting effect
  • Bio-stimulation of elastin and collagen
  • Active Acne treatment
  • Acne scarring improvement
  • Hair growth stimulation

Unlock Your Skin’s Potential at Our Premier Harley Street Clinic in London

Recent studies have shown that Polynucleotides Skin Boosters can increase skin hydration by up to 30% and improve skin elasticity by up to 25% after a series of treatments.

This product is a combination of the most effective ingredients for revitalisation- polynucleotides (PDRN), niacinamide, and hyaluronic acid. Crystal PDRN stimulates the formation of tissue and cell division while helping improve the overall appearance of the skin within a period of time.

Effects

  • Promotes cell regeneration
  • Renews radiance and smoothness of skin tone
  • Improves skin elasticity
  • Balances inner skin layer
  • Replenishes moisture
  • Provides anti-aging effect
  • Improves micro wrinkles
  • Creates a clean and clear complexion for patients by increasing moisture within the skin

An initial course of 3 treatments is required, 3-4 weeks apart for optimal results. After the intensive course, a repeat treatment is advised every 4-6 months to further maintain and enhance skin quality.

Side Effects

  • Needle marks
  • Possible bruising
  • Skin sensitivity

No significant other side effects have been reported. Adverse effects of this product are extremely rare.

Cost

1 session £375
3 sessions £1000

Nucleofill is a product based on active polynucleotides specially designed for skin renewal and bio-restructuring. This product is not intended for adding volume. The natural polynucleotide-based bio-stimulating gels, with high viscosity, are designed to protect and rejuvenate the skin. It is compatible with a mesotherapy protocol.

Effects

  • Provides a visible rejuvenating effect without affecting facial features
  • Reduces the appearance of wrinkles and creases and firms the skin
  • Improves skin texture of skin exposed to oxidative stress (due to air pollution, sun exposure, smoking, poor diet)
  • Replenishes dehydrated skin
  • Extends the efficacy and effects of other aesthetic products. It is used to prepare the skin before injections.
  • Has a lifting effect

It’s recommended to have 2 treatments with 2-4 weeks in between each session, in severe cases you can have up to 4 treatments within 2-4 weeks intervals.

Side Effects

  • Bruising may occur
  • Some swelling in the injection area 1-2 days

No other side effects have been reported.

Cost:

1 session £450
2 sessions £800
4 sessions £1500

Rejuran Healer (PN) is a treatment designed for skin healing and rejuvenation. It contains highly bio-compatible DNA fragments (polynucleotides), to improve the overall condition of damaged/ageing skin. Rejuran Healer is indispensable in the treatment of acne, as well as in post-acne procedures aimed at restoring the skin and giving it a smooth and healthy tone.

Effects

  • Recovers damaged cells and stimulates repair processes
  • Improves the elasticity of the skinRestores microcirculation in tissue
  • Reduces the process of inflammatory manifestation of acne
  • Promotes narrowing of pores
  • Accelerates healing and scarring of the skin
  • Increases the metabolic activity of cells, preventing the formation of new wrinkles

It is recommended to have 4 sessions at 3-4 week intervals. Results may take up to a month post the last treatment depending on the genetic and environmental factors of each individual.

Side Effects

  • Redness
  • Little red bumps at the injection points that subside over 12-24 hours
  • Slight bruising may occur

No other side effects have been reported due to Rejuran’s highly bio-compatible nature.

Prices:

1 session £375
4 sessions £1300

  • Concentration of PN
  • Additional ingredients such as hyaluronic acid and vitamins
  • PN or PDRN
  • The amount available for treatment
  • The delivery ie technique of administration

The product and type of polynucleotide skin boosters should be selected on an individual basis after a consultation with a Skin Logic Aesthetics clinic practitioner. A higher concentration is not always the best option. A higher concentration of PN is better for the under-eye area, whereas PDRN is often better for a whole-face skin improvement, especially when ageing signs are present.

Cells in our body are home to genetic material which are responsible for giving instructions needed for our organism to survive and reproduce. Our genetic material is formed of RNA and DNA and Both are made up of subunits called nucleotides.

Polynucleotides are therefore molecule composed of many nucleotide units. Now Fibroblasts are a type of cell in connective tissues that produce collagen and help maintain the structural framework of tissues.
As we age, the function of Fibroblast reduces, leading to decrease in collagen production leading to wrinkles and skin laxity.

When injected into the skin, polynucleotides allow more fibroblasts to be regenerated , stimulated and produce more collagen.

The longevity of Polynucleotide therapy results is one of its most compelling aspects and general observations suggest that the most noticeable changes become visible in the 9 months following treatment.

The Polynucleotide therapy works by activating your skin’s natural regenerative processes, leading to long-term improvements in skin health and aesthetics.
However, the results are not permanent, as the skin continues to age naturally. To maintain and enhance these results, we recommend scheduling follow-up treatments based on your skin’s needs and your aesthetic goals.

Repeated treatments allow the Polynucleotides to continually stimulate your skin’s healing and rejuvenation processes, leading to more pronounced and sustained improvements.
With Polynucleotide therapy, you’re not just investing in a one-time aesthetic treatment. You’re investing in long-term skin health and enhancement, empowering you to face the future with confidence and radiance.

At our state-of-the-art clinic in Harley Street, London, our expert practitioners follow a meticulous process to ensure optimal results:

  • Consultation: We’ll assess your skin and discuss your goals to create a personalized treatment plan.
  • Preparation: The treatment area is cleansed and may be numbed with a topical anesthetic.
  • Injection: Using ultra-fine needles, the Polynucleotides solution is skillfully administered into multiple points across the treatment area.
  • Post-Treatment Care: You’ll receive detailed aftercare instructions to maximize results and minimize side effects.
  • Follow-up Sessions: We’ll schedule subsequent treatments, typically 2-4 weeks apart, for optimal results.

To ensure the best possible results from your Polynucleotides Skin Booster treatment in London, follow these guidelines:

Before Your Treatment:

  • Avoid blood-thinning medications and supplements for a week prior (unless medically necessary)
  • Refrain from alcohol consumption for 24 hours before treatment
  • Come to your appointment with clean skin, free of makeup
  • Stay well-hydrated in the days leading up to your treatment

After Your Treatment:

  • Avoid touching or massaging the treated areas for 24 hours
  • Skip intense exercise for 24 hours post-treatment
  • Avoid excessive heat exposure (saunas, hot showers) for 24 hours
  • Stay hydrated to optimise results
  • Follow any specific skincare recommendations provided by your practitioner
  • Attend all scheduled follow-up appointments for optimal results
Make an Enquiry
Book an Appointment

FAQs

Are there any side effects / risks with Polynucleotides?

Unlike with some traditional dermal filler treatments, there is no risk of occlusion, permanent lumping, blindness or other related complications with Polynucleotides. The product is extremely pure and to date, there have been no adverse reactions to the product.

Is there any downtime following a treatment with Polynucleotides?

There is no clinical downtime with this treatment. However, as with any injectable procedure, you might experience some slight bruising, swelling or tenderness at the injection sites, but this should subside within a few days.

Are Polynucleotides the same as dermal fillers?

No – dermal fillers are made from hyaluronic acid, which fills an area and attracts water, whereas injectable Polynucleotide serum doesn’t fill the space. It does have a moisturising effect by attracting water, but also acts as an antioxidant and an internal messenger, signalling to the dermis to grow new skin cells.

What can Polynucleotides be used for?

Due to their restorative action, Polynucleotides can treat a variety of skin concerns, including:

  • Acne and acne scarring
  • General signs of ageing (fine and deeper lines and wrinkles)
  • Trauma or surgical scarring
  • Dehydrated skin
  • Sagging skin losing elasticity
  • Rosacea
  • Hair loss (alopecia)
  • Hyperpigmentation and sun damage
  • Stretch marks

Areas that can be treated with Polynucleotides include the entire face and neck, décolleté, the eye area (they offer an alternative to dermal filler tear trough treatment), abdomen, arms and knees.

As a natural, regenerative injectable, Polynucleotides can also be used safely in conjunction with other injectables and skin treatments. These typically include laser resurfacing, radiofrequency, dermal fillers, signature facials, anti-wrinkle treatments and ultrasound treatments.

What is the difference between Polynucleotide treatment and other skin boosters such as Profhilo?

Polynucleotides represent the next generation of skin boosters. They offer the same or better results as Profhilo (made from Hyaluronic Acid), but are made from DNA fragments which stimulate fibroblasts in the skin. PDRNs also have an anti-inflammatory effect, removing free radicals from the dermis.

Profhilo is a better hydrator of the skin than Polynucleotides are, and gives a dewy glow to the skin. Polynucleotide treatments like Juvenus, Nucleofill and Plenyhage offer a similar effect and are a great option in areas such as the under-eye, where too much water attraction isn’t wanted.

Are Polynucleotides Skin Booster injections painful?

Most patients report minimal discomfort during the treatment. We use ultra-fine needles to administer the solution, and a topical anesthetic can be applied if needed. Some patients describe a slight stinging sensation during injection, but this is generally well-tolerated and subsides quickly. After the treatment, you may experience some mild tenderness in the treated areas, but this typically resolves within a day or two.

How many treatments will I need?

The number of treatments required can vary depending on your individual skin concerns and goals. Typically, we recommend a series of 3 treatments spaced 2-4 weeks apart for optimal results. This protocol allows for cumulative improvements in skin quality. After the initial series, maintenance treatments every 4-6 months can help sustain the results. During your consultation, we’ll assess your skin and create a personalized treatment plan tailored to your needs.

Can Polynucleotides be combined with other treatments?

Yes, Polynucleotides Skin Boosters can complement a variety of other aesthetic treatments. They work particularly well in combination with treatments like Botox for wrinkle reduction, dermal fillers for volume restoration, or laser therapies for skin resurfacing. The skin-boosting effects of Polynucleotides can enhance the results of these other treatments by improving overall skin quality. During your consultation, we can discuss a comprehensive treatment plan that combines different modalities to address all your skin concerns effectively.

How do Polynucleotides Skin Boosters differ from other skin treatments?

Polynucleotides Skin Boosters offer a unique approach to skin rejuvenation. Unlike traditional dermal fillers that add volume, or Botox which relaxes muscles, Polynucleotides work by stimulating your skin’s natural regenerative processes. They improve overall skin quality rather than targeting specific wrinkles or folds. The DNA fragments in Polynucleotides promote cellular renewal and collagen production, leading to more comprehensive and natural-looking improvements in skin texture, hydration, and elasticity. This makes them an excellent choice for overall skin rejuvenation or as a complementary treatment to other aesthetic procedures.

All treatments are tailored to the individual and personal experiences and results may vary. We recommend a one to one consultation with our expert practitioners to discuss your treatment options.

Book a Free Consultation →

Treatment Price Banner - Sand
Polynucleotides Skin Boosters Treatment Harley Street

Third Generation Polynucleotides Skin Boosters

Crystal PDRN

1 session £375
3 sessions £1000

Nucleofill

1 session £450
2 sessions £800
4 sessions £1500

Rejuran Healer

1 session £375
4 sessions £1300

Learn more about our

Polynucleotides Skin Boosters in London

Experience the transformative power of Polynucleotides Skin Boosters at our prestigious Harley Street clinic in London. Our expert team is dedicated to helping you achieve radiant, healthy-looking skin that glows from within. Book your consultation today and take the first step towards a more luminous you!
Make an Enquiry
Book an Appointment

Related
Treatments

Related
Posts

Articles and Posts we think would help you get a better insight on to the treatment.

Read all →

Skin Logic Banner Image

I have some quetions...

Please enable JavaScript in your browser to complete this form.
January Special Offer Now On!
View Offers
January Special Offer Now On!