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Polynucleotide
Under Eyes

Q: Preparation and Aftercare

Before Treatment: Avoid blood-thinning supplements (Vitamin E, Fish Oil) and alcohol for 24 hours. Arrive with a clean face, free of makeup if possible. Aftercare: Do not apply makeup to the area for 12 hours. Avoid strenuous exercise, saunas, and steam rooms for 48 hours. Gently sleep with an extra pillow to reduce any initial morning swelling. Apply a high-factor SPF to protect the treated area from UV damage.

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Advanced Polynucleotide Treatment for Eye Rejuvenation - Nucleofill Eyes

Refresh your appearance with Nucleofill Eyes, a revolutionary polynucleotide-based injectable designed specifically for the delicate periocular area. This bio-restructuring treatment goes beyond traditional fillers to repair, hydrate, and firm the skin from within, effectively tackling dark circles, puffiness, and fine lines for a naturally radiant look. New to polynucleotides? Read our polynucleotides under the eyes guide first.

This polynucleotide under eyes treatment delivers remarkable aesthetic outcomes through advanced medical science. The treatment stimulates natural collagen production whilst improving skin texture, elasticity, and hydration levels around the delicate eye area. Nucleofill Eyes contains polynucleotides – naturally occurring compounds that stimulate cellular repair and regeneration at the molecular level. The polynucleotide injection technique delivers these active compounds directly into the targeted tissue, where they work to:

Stimulate fibroblast activity for enhanced collagen synthesis
Improve cellular metabolism and tissue oxygenation
Enhance natural hyaluronic acid production for optimal hydration
Promote healthy tissue remodelling and repair processes

Benefits of Nucleofill Eyes

Reduction of fine lines and crow’s feet through cellular regeneration
Significantly reduces the appearance of dark circles and vascular shadows
Enhanced skin quality and improved texture around the periorbital region
Natural-looking results that complement your facial features
Minimal recovery time allowing swift return to daily activities
Stimulates collagen and elastin production at a cellular level
Polynucleotides bind with water to provide long-lasting moisture
Strengthens the thin, fragile skin around the eyes to reduce “crepiness”
Provides a powerful antioxidant effect to protect against environmental damage

When Should You Consider This Treatment?

Nucleofill Eyes is an ideal solution if you are experiencing:

Dark circles or “tear trough” shadows
Puffiness or bags under the eyes
Fine lines, wrinkles, or “Crow’s Feet”
Thin, dehydrated, or crepey skin around the eyelids
A desire for a natural-looking rejuvenation without the “puffy” look sometimes associated with fillers

Our specialist practitioners carefully evaluate individual goals and physical characteristics when recommending treatment protocols, ensuring optimal outcomes for each patient.

Polynucleotides are increasingly preferred over fillers for the eye area

This aesthetic concern is often caused by the thinning of the dermis, which makes the underlying blood vessels more visible. Research published in the Journal of Cosmetic Dermatology highlights that bio-stimulating treatments like Polynucleotides are increasingly preferred over fillers for this area because they address the root cause—skin quality—rather than just masking the symptoms.

How Nucleofill Eyes Helps Patients

Our polynucleotide under eyes therapy addresses multiple aesthetic concerns simultaneously. Patients benefit from improved skin quality, reduced visible signs of ageing, and enhanced confidence in their appearance.

The treatment specifically targets:

Volume Loss: Restoring natural fullness to hollow or sunken areas beneath the eyes through tissue regeneration.

Skin Quality: Improving texture, tone, and elasticity whilst reducing the appearance of fine lines and wrinkles.

Hydration Levels: Enhancing the skin’s natural moisture retention capabilities for a more youthful, refreshed appearance.

Dark Circles: Addressing underlying tissue quality issues that contribute to periorbital discolouration and shadowing.

The Treatment Process: What to Expect

Your journey begins with a bespoke consultation at Skinlogica Aesthetics to ensure Nucleofill is the right choice for you.

Preparation: The eye area is thoroughly cleansed. A topical numbing cream may be applied for your comfort.

The Procedure: Using a very fine needle or a blunt cannula, the Polynucleotide gel is precisely injected into the periocular area.

Completion: A light massage is performed to ensure even distribution. You may notice small bumps (papules) which are normal and typically subside within 24 hours as the product absorbs.

Preparation and Aftercare

Before Treatment:

Avoid blood-thinning supplements (Vitamin E, Fish Oil) and alcohol for 24 hours.
Arrive with a clean face, free of makeup if possible.

Aftercare:

Do not apply makeup to the area for 12 hours.
Avoid strenuous exercise, saunas, and steam rooms for 48 hours.
Gently sleep with an extra pillow to reduce any initial morning swelling.
Apply a high-factor SPF to protect the treated area from UV damage.

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FAQs

Is Nucleofill Eyes the same as a tear trough filler?

No. While fillers use Hyaluronic Acid to add volume, Nucleofill uses Polynucleotides to repair and thicken the skin. It is often a safer alternative for those prone to puffiness.

Does the treatment hurt?

Most clients describe the sensation as a light stinging or pressure. We use ultra-fine needles and can apply numbing cream to ensure the process is as comfortable as possible.

Are there any side effects?

Common side effects include mild swelling, redness, or bruising at the injection site. These are temporary and usually resolve within 1–3 days.

Can I combine this with Botox?

Yes! Nucleofill improves skin quality, while Botox relaxes the muscles that cause wrinkles. They work excellently together for a total eye rejuvenation.

Is there any downtime?

Downtime is minimal. You can return to work almost immediately, though you may have slight swelling for the first 24 hours.

Is Nucleofill safe?

Yes. Polynucleotides are naturally occurring substances and have been used in various medical fields for decades to promote tissue healing.

Who is not suitable for this treatment?

It is not recommended for those who are pregnant or breastfeeding, or those with a known fish allergy (as PN is often derived from salmon DNA). Additional contraindications include active skin infections, autoimmune conditions, and certain blood clotting disorders.

How long do the results last?

Results typically last 6-12 months, with individual variation based on skin type, lifestyle factors, and natural ageing processes. We recommend a single maintenance session every 6 months to keep the area looking fresh.

When will I see the final results?

While you may notice a “glow” quickly, the structural changes (collagen production) take time. You will see the full transformative effect about 4 weeks after your final session.

Can polynucleotides be used on eyelids?

Yes, polynucleotides can be safely used on eyelids when administered by qualified practitioners. The treatment is specifically formulated for the delicate periorbital area.

How does this compare to other eye treatments?

Nucleofill Eyes offers unique advantages through cellular regeneration rather than simple volume replacement, providing more natural, long-lasting improvements.

All treatments are tailored to the individual and personal experiences and results may vary. We recommend a one to one consultation with our expert practitioners to discuss your treatment options.

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Nucleofill Eyes Pricing

1 Vial	£450
2 Vials	£840
3 Vials	£1200

Learn more about our

Nucleofill Eyes Treatment in London

Ready to brighten your gaze and restore confidence in your skin? Our expert team is here to help you achieve natural, long-lasting results with the latest in polynucleotide technology. [Click here to book your consultation] or contact us today to learn more about how Nucleofill Eyes can transform your appearance.

Make an Enquiry

Book an Appointment